Huda Y Zoghbi Selected Research

Rett Syndrome (Rett's Disorder)

1/2021	Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome.
11/2020	MeCP2 Levels Regulate the 3D Structure of Heterochromatic Foci in Mouse Neurons.
1/2020	Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia.
1/2020	Advances in understanding of Rett syndrome and MECP2 duplication syndrome: prospects for future therapies.
12/2019	The distinct methylation landscape of maturing neurons and its role in Rett syndrome pathogenesis.
11/2019	Mecp2 Deletion from Cholinergic Neurons Selectively Impairs Recognition Memory and Disrupts Cholinergic Modulation of the Perirhinal Cortex.
1/2018	Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity.
8/2016	Loss and Gain of MeCP2 Cause Similar Hippocampal Circuit Dysfunction that Is Rescued by Deep Brain Stimulation in a Rett Syndrome Mouse Model.
11/2015	Loss of MeCP2 in Parvalbumin-and Somatostatin-Expressing Neurons in Mice Leads to Distinct Rett Syndrome-like Phenotypes.
10/2015	Rett syndrome: disruption of epigenetic control of postnatal neurological functions.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Huda Y Zoghbi Research Topics

Disease

52	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2022 - 01/2002
38	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 01/2002
31	Rett Syndrome (Rett's Disorder) 01/2021 - 01/2002
15	Neurodevelopmental Disorders 01/2020 - 01/2002
10	Ataxia (Dyssynergia) 01/2021 - 05/2006
8	Intellectual Disability (Idiocy) 01/2020 - 01/2006
7	Parkinson Disease (Parkinson's Disease) 01/2021 - 09/2014
5	Nervous System Diseases (Neurological Disorders) 11/2019 - 07/2011
5	Autistic Disorder (Autism) 05/2018 - 01/2006
3	Lubs X-linked mental retardation syndrome 01/2021 - 05/2018
3	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 10/2016
3	Autism Spectrum Disorder 10/2016 - 09/2008
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2022 - 04/2015
2	Proteostasis Deficiencies 10/2016 - 03/2015
2	Huntington Disease (Huntington's Disease) 03/2005 - 11/2003
2	Disease Progression 10/2004 - 01/2002
1	Mental Disorders (Mental Disorder) 01/2022
1	Memory Disorders (Memory Loss) 01/2021
1	Glioblastoma (Glioblastoma Multiforme) 01/2020
1	Developmental Disabilities (Developmental Disability) 12/2019
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2018
1	Chromosome 15q13.3 Microdeletion Syndrome 01/2018
1	Neoplasms (Cancer) 11/2017
1	Brain Neoplasms (Brain Tumor) 11/2017
1	Medulloblastoma 11/2017
1	Apnea 04/2017
1	Hearing Loss (Hearing Impairment) 01/2017
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 10/2016
1	Fragile X Syndrome (Martin Bell Syndrome) 04/2015
1	Cholestasis 02/2015
1	Inflammation (Inflammations) 02/2015
1	Microcephaly 10/2014
1	Alacrima 10/2014
1	Seizures (Absence Seizure) 10/2014
1	Mycoses (Diseases, Fungus) 12/2012
1	Schizophrenia (Dementia Praecox) 11/2010
1	Cognitive Dysfunction 11/2010
1	Brain Diseases (Brain Disorder) 11/2010
1	Spinocerebellar Ataxia 10 06/2010

Drug/Important Bio-Agent (IBA)

41	polyglutamineIBA 01/2022 - 01/2002
34	Ataxin-1IBA 01/2022 - 01/2002
32	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2002
29	Methyl-CpG-Binding Protein 2IBA 01/2021 - 01/2002
8	Glutamine (L-Glutamine)FDA Link 11/2018 - 04/2005
5	Mutant Proteins (Protein, Mutant)IBA 03/2015 - 06/2002
4	SynucleinsIBA 01/2021 - 01/2018
4	Serine (L-Serine)FDA Link 01/2017 - 05/2003
3	Phosphotransferases (Kinase)IBA 01/2021 - 05/2013
3	RNA (Ribonucleic Acid)IBA 11/2018 - 07/2010
3	DNA (Deoxyribonucleic Acid)IBA 04/2015 - 01/2002
3	AtaxinsIBA 07/2010 - 10/2004
2	Antisense OligonucleotidesIBA 01/2021 - 11/2018
2	Nuclear Proteins (Protein, Nuclear)IBA 11/2020 - 09/2003
2	LithiumIBA 01/2013 - 05/2007
2	Biological ProductsIBA 02/2011 - 04/2005
1	MicroRNAs (MicroRNA)IBA 01/2020
1	5' Untranslated Regions (5' UTR)IBA 01/2020
1	Poly AIBA 01/2020
1	Cholinergic Agents (Cholinergics)IBA 11/2019
1	Peptides (Polypeptides)IBA 01/2019
1	Amyloid (Amyloid Fibrils)IBA 01/2019
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 01/2018
1	Deubiquitinating EnzymesIBA 01/2018
1	Transcription Factors (Transcription Factor)IBA 11/2017
1	Tyrosine (L-Tyrosine)FDA Link 11/2017
1	SodiumIBA 04/2017
1	alpha-SynucleinIBA 10/2016
1	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 11/2015
1	ParvalbuminsIBA 11/2015
1	ChromatinIBA 10/2015
1	Fragile X Mental Retardation ProteinIBA 04/2015
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2015
1	Transaminases (Aminotransferases)IBA 10/2014
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 05/2013
1	PurinesIBA 01/2013
1	LipidsIBA 01/2013
1	Glucose (Dextrose)FDA LinkGeneric 01/2013
1	purineIBA 01/2013
1	InterferonsIBA 12/2012
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 01/2012
1	Epidermal Growth Factor (EGF)IBA 11/2011
1	Q-Type Calcium Channels (Q-Type Calcium Channel)IBA 02/2011
1	Ataxin-7IBA 02/2011
1	gamma-Aminobutyric Acid (GABA)IBA 11/2010
1	Aminobutyrates (Aminobutyric Acid)IBA 11/2010
1	Small Interfering RNA (siRNA)IBA 06/2010
1	Caspase 3 (Caspase-3)IBA 06/2010
1	Ataxin-10IBA 06/2010
1	Heterogeneous-Nuclear Ribonucleoprotein KIBA 06/2010
1	CalciumIBA 08/2008
1	voltage-dependent calcium channel (P-Q type)IBA 08/2008
1	Insulin-Like PeptidesIBA 01/2008

Therapy/Procedure

11	Therapeutics 01/2022 - 04/2005
5	Deep Brain Stimulation 01/2018 - 09/2014
1	Precision Medicine 01/2022
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2018
1	Mechanical Ventilators (Ventilator) 01/2018
1	Drug Therapy (Chemotherapy) 11/2017
1	Immunotherapy 12/2015
1	Airway Management 12/2012